GLP-1 Weight Loss Guides & FAQ
Straight answers about semaglutide and tirzepatide weight loss, sourced from published clinical-trial data rather than anecdotes.
How much weight can you lose on semaglutide vs. tirzepatide?
In published trials, semaglutide (STEP 1) produced average total body-weight reduction of about 14.9% at 68 weeks, while tirzepatide at its highest studied dose (SURMOUNT-1) produced about 20.9% at 72 weeks. These are trial averages, not guarantees, individual results vary.
Read the full guideHow long does it take to see results on a GLP-1 medication?
Most people see early weight loss within the first month, with the rate of loss gradually slowing as the body approaches its plateau, typically reached over 60-72 weeks in clinical trials.
Read the full guideHow does the GLP-1 weight loss calculator work?
The calculator projects a month-by-month timeline from your current weight toward your goal weight, using an approach-to-plateau curve calibrated to the average outcomes reported in the STEP 1 and SURMOUNT-1 clinical trials.
Read the full guideMore Guides
- What Is GLP-1?
- GLP-1 Pills vs. Injections
- Do GLP-1 Patches, Gummies, and Drops Work?
- GLP-1 Side Effects
- GLP-1 Medications List
- How Much Does GLP-1 Cost?
- Agonists vs. Antagonists vs. Inhibitors
- GLP-1 Before and After
- GLP-1 Injection Sites
- GLP-1 Microdosing
- Is GLP-1 Safe?
- GLP-1 and Hair Loss
Want a personalized estimate based on your own numbers?
Try the Free GLP-1 Calculator